2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds

ABSTRACT

The present application relates to novel 2-(4-piperidinyl)-1H-pyrido[4,3-b]indol-1-ones of formula &lt;CHEM&gt; wherein R&lt;1&gt; is hydrogen, optionally substituted phenyl or phenylalkyl, R&lt;2&gt; is hydrogen, alkyl, furanylalkyl, thienylalkyl, pyrrolylalkyl, pyridinylalkyl, optionally substituted phenylalkyl or a group of formula &lt;CHEM&gt; wherein R&lt;3&gt; is alkyl, haloalkyl, haloalkyl or optionally substituted phenyl or phenylalkyl; X is hydrogen, alkyl, alkoxy, halogen, or trifluoromethyl; m is 0, 1, or 2; n is 1 or 2. The compounds of the invention show antipsychotic acitvity and can therefore be used as medicaments.



